It doesn't really help unless you have tons of attackspeed and/or Silver charged Shadow Clone. Maybe combined with the Berserk skill it could work but I would rather go damage than attackspeed while using a 2handed weapon.Does it actually help? I've tried it with and without, but the EP regen feels the same. I guess I thought it would work like Berserk.
It doesn't really help unless you have tons of attackspeed and/or Silver charged Shadow Clone. Maybe combined with the Berserk skill it could work but I would rather go damage than attackspeed while using a 2handed weapon.
Edit: You're saying regen but it doesn't effect your passive regen. I assumed that you knew that but you might have missed it in which case my response would make no sense at all.
Unless you want to spend milions of hours on fishing to get attackspeed from your pet aswell as crit I don't think there's much to do with a 2handed setup. Maybe with the Support skill that boosts attackspeed combined with as much attackspeed equipment you can have without losing out on the crit stats could get you to a decent attackspeed that with attack cancelling could sustain your mana but I highly doubt it would work.